The Italian was sent off for violent conduct against Real Madrid for punching Eder Militao in the leg and he will miss the Round of 16 clash with Liverpool.
The Champions League draw was redone and Inter were confirmed as the Reds’ opponent for the next round in Europe.
They finished second in Group D behind Los Blancos after winning just three of their games. They lost two and drew one, finishing on 10 points from a possible 18.
Barella, a player so talented he was actually linked with Liverpool in the summer, will be a major miss for Inter. His straight red card means he should be unavailable for selection unless Inter Milan are successful with any appeals.
In July, FC Inter News cited a report from daily paper La Repubblica which claimed that Liverpool had submitted a €70million (£60m) bid to sign him.
The Italian was incredible at the EUROs as Italy won the tournament, and this season, he has one goal and eight assists in all competitions.
It sounds cocky but it doesn’t matter who Inter field against Liverpool. Jurgen Klopp’s side has proved to be a test for any and all they have faced.
If the German has a fully fit squad to face the Serie A champions, I’m fully confident they will progress to the next round quite comfortably.
Last season was something of a fluke due to injuries but, under Klopp, Liverpool have shown again that they are a European heavyweight.
It’s going to be a fascinating clash and will be really interesting to see how the two sides try to outsmart each other.
At the end of the day, it could be decided by a moment of brilliance from any one of Salah, Mane, Trent or a number of other influential Liverpool stars.