The league leaders make the trip to Anfield commanding a seven-point lead over the reigning champions, having played a game less.
Liverpool themselves, are without a win in their previous four matches at Anfield, too.
The Reds recently surrendered their 68-match unbeaten run at home to Burnley a fortnight ago. Jurgen Klopp and his team were beaten again on their own turf on Wednesday.
So, the need for Liverpool to get a result against City is suddenly increased, then. It’s fair to assume that the Reds’ diminishing title prospects could effectively be over or reignited come to the final whistle on Sunday.
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City are currently enjoying a nine-match winning run, with a 2-0 victory against Burnley on Tuesday night their most recent success story.
However, City will be without the likes of key players such as Aguero, Ake and last season’s PFA Player of the Year, Kevin de Bruyne.
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This is a major positive for Liverpool, ahead of what is arguably their toughest match of the season so far.
Our chances of retaining the title currently hang by a thread, but City’s absence of key personnel coupled by the returns of Sadio Mane, Alisson Becker and Fabinho will increase Liverpool’s chances of upsetting the apple-cart come Sunday.
With Fabinho back in the mix, Liverpool finally have the luxury of potentially move Jordan Henderson back into his preferred midfield role.
Ozan Kabak, too, could make a Premier League debut against the Citizens, after he was given international clearance to be selected in Klopp’s squad.
There is, then, a lot of anticipation as well as a number of possibilities to how the team could shape up come Sunday afternoon.