Liverpool manager Jurgen Klopp has some seriously tough selection decisions to make against West Ham.
Further injury setbacks for the Reds have complicated matters for Klopp with a whole host of changes expected from the team that beat FC Midtjylland in midweek.
One alteration is necessary, with Fabinho unlikely to feature following his hamstring issue on Wednesday night.
Fortunately, Liverpool could see the return of Thiago Alcantara to raise spirits following another defensive setback that adds to an injury list that also includes Virgil van Dijk and Joel Matip.
The Spaniard has been confirmed as in contention to make his first Anfield appearance against the Hammers on Saturday, the Evening Standard has confirmed.
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Rhys Williams is also likely to make his Premier League debut having replaced Fabinho during the 2-0 Champions League win on Wednesday.
The first big question is really whether Liverpool go with a 4-3-3 formation or stick with the 4-2-3-1 system that has inspired back-to-back victories in the league and in Europe.
Given the number of injuries, the back-four is likely to pick itself with Joe Gomez and Williams partnered in the heart of the defence with Andy Robertson and Trent Alexander-Arnold taking their typical full-back duties.
Central midfield is a big debate especially when you factor in the return of Thiago. At least one of Jordan Henderson or Georginio Wijnaldum should start after the success of the last two games – but if he is fit we expect the Spaniard to go straight back into the starting XI.
The attacking quartet could stay the same also with Mohamed Salah leading the line again, with Sadio Mane, Roberto Firmino and Diogo Jota providing support.
If Liverpool go for their tried-and-tested system, it is probable that one of the attackers will drop out, although who that could be remains to be seen.
Midfield once again is a contentious choice, but for the sake of consistency here we will go with a triumvirate of Thiago, Henderson and Wijnaldum.
Selecting Jota as opposed to Firmino would be a big call from Klopp although given the manager is yet to drop any of his pedigreed front-three for a league match makes the Portugal international the likely casualty to come out should Klopp opt for a 4-3-3.
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